diff --git a/pkgs/development/compilers/gcc/5/default.nix b/pkgs/development/compilers/gcc/5/default.nix
index ea59d2826e2..3c0a0e675d5 100644
--- a/pkgs/development/compilers/gcc/5/default.nix
+++ b/pkgs/development/compilers/gcc/5/default.nix
@@ -258,13 +258,14 @@ stdenv.mkDerivation ({
       let
         libc = if libcCross != null then libcCross else stdenv.cc.libc;
       in
-        '' echo "fixing the \`GLIBC_DYNAMIC_LINKER' and \`UCLIBC_DYNAMIC_LINKER' macros..."
+        '' echo "fixing the \`GLIBC_DYNAMIC_LINKER', \`UCLIBC_DYNAMIC_LINKER', and \`MUSL_DYNAMIC_LINKER' macros..."
            for header in "gcc/config/"*-gnu.h "gcc/config/"*"/"*.h
            do
              grep -q LIBC_DYNAMIC_LINKER "$header" || continue
              echo "  fixing \`$header'..."
              sed -i "$header" \
-                 -e 's|define[[:blank:]]*\([UCG]\+\)LIBC_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define \1LIBC_DYNAMIC_LINKER\2 "${libc.out}\3"|g'
+                 -e 's|define[[:blank:]]*\([UCG]\+\)LIBC_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define \1LIBC_DYNAMIC_LINKER\2 "${libc.out}\3"|g' \
+                 -e 's|define[[:blank:]]*MUSL_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define MUSL_DYNAMIC_LINKER\1 "${libc.out}\2"|g'
            done
         ''
     else null;
@@ -396,6 +397,7 @@ stdenv.mkDerivation ({
       # On Illumos/Solaris GNU as is preferred
       "--with-gnu-as" "--without-gnu-ld"
     ]
+    ++ optional (targetPlatform == hostPlatform && targetPlatform.libc == "musl") "--disable-libsanitizer"
   ;
 
   targetConfig = if targetPlatform != hostPlatform then targetPlatform.config else null;
diff --git a/pkgs/development/compilers/gcc/6/default.nix b/pkgs/development/compilers/gcc/6/default.nix
index 78062ea4bb1..7fb2eec3f77 100644
--- a/pkgs/development/compilers/gcc/6/default.nix
+++ b/pkgs/development/compilers/gcc/6/default.nix
@@ -260,13 +260,14 @@ stdenv.mkDerivation ({
       let
         libc = if libcCross != null then libcCross else stdenv.cc.libc;
       in
-        '' echo "fixing the \`GLIBC_DYNAMIC_LINKER' and \`UCLIBC_DYNAMIC_LINKER' macros..."
+        '' echo "fixing the \`GLIBC_DYNAMIC_LINKER', \`UCLIBC_DYNAMIC_LINKER', and \`MUSL_DYNAMIC_LINKER' macros..."
            for header in "gcc/config/"*-gnu.h "gcc/config/"*"/"*.h
            do
-             grep -q LIBC_DYNAMIC_LINKER "$header" || continue
+             grep -q _DYNAMIC_LINKER "$header" || continue
              echo "  fixing \`$header'..."
              sed -i "$header" \
-                 -e 's|define[[:blank:]]*\([UCG]\+\)LIBC_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define \1LIBC_DYNAMIC_LINKER\2 "${libc.out}\3"|g'
+                 -e 's|define[[:blank:]]*\([UCG]\+\)LIBC_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define \1LIBC_DYNAMIC_LINKER\2 "${libc.out}\3"|g' \
+                 -e 's|define[[:blank:]]*MUSL_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define MUSL_DYNAMIC_LINKER\1 "${libc.out}\2"|g'
            done
         ''
     else null;
diff --git a/pkgs/development/compilers/gcc/7/default.nix b/pkgs/development/compilers/gcc/7/default.nix
index 267e660e12d..73768d65104 100644
--- a/pkgs/development/compilers/gcc/7/default.nix
+++ b/pkgs/development/compilers/gcc/7/default.nix
@@ -254,13 +254,14 @@ stdenv.mkDerivation ({
       let
         libc = if libcCross != null then libcCross else stdenv.cc.libc;
       in
-        '' echo "fixing the \`GLIBC_DYNAMIC_LINKER' and \`UCLIBC_DYNAMIC_LINKER' macros..."
+        '' echo "fixing the \`GLIBC_DYNAMIC_LINKER', \`UCLIBC_DYNAMIC_LINKER', and \`MUSL_DYNAMIC_LINKER' macros..."
            for header in "gcc/config/"*-gnu.h "gcc/config/"*"/"*.h
            do
              grep -q LIBC_DYNAMIC_LINKER "$header" || continue
              echo "  fixing \`$header'..."
              sed -i "$header" \
-                 -e 's|define[[:blank:]]*\([UCG]\+\)LIBC_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define \1LIBC_DYNAMIC_LINKER\2 "${libc.out}\3"|g'
+                 -e 's|define[[:blank:]]*\([UCG]\+\)LIBC_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define \1LIBC_DYNAMIC_LINKER\2 "${libc.out}\3"|g' \
+                 -e 's|define[[:blank:]]*MUSL_DYNAMIC_LINKER\([0-9]*\)[[:blank:]]"\([^\"]\+\)"$|define MUSL_DYNAMIC_LINKER\1 "${libc.out}\2"|g'
            done
         ''
     else null;
@@ -392,6 +393,7 @@ stdenv.mkDerivation ({
       # On Illumos/Solaris GNU as is preferred
       "--with-gnu-as" "--without-gnu-ld"
     ]
+    ++ optional (targetPlatform == hostPlatform && targetPlatform.libc == "musl") "--disable-libsanitizer"
   ;
 
   targetConfig = if targetPlatform != hostPlatform then targetPlatform.config else null;